Hi,
Given you've lived here before, you have some good knowledge of many things already. Check old posts and drop all the questions you want if things aren't covered or are out of date etc and I'm sure you'll get excellent responses.
Now you have kids, there will be a shift in focus and what you will want given that dynamic. Evaluate and research carefully, compare with the realistic budget levels you'll have and also look at the mess that is Brexit and if you'll be in industries which might be more adversely affected etc. If you do deem it might be more problematic in the future due to that, I'd suggest looking to other countries if possible and/or remaining in the USA. That president chump should be out of office soon and then the USA can hopefully put someone much better in place!
Cheers, DtM! West London & Slough UK!