It ain't easy, that's for sure. You'll find a bunch of other threads around here complaining about house prices.
What will you be doing with your house in the US? If you're selling it, that should give you a nice start. The amount of your down payment makes a big difference on the type of loan you can get and the interest rate. The best advice I have based on our current experience is start saving up some money to use for an initial payment. Even if its only 5% of the total it makes a big difference, and more is better.
There are 100% loans, although with no UK credit they are tough to get. (as I've found out...

) If your husband is English perhaps he could open a bank account or get a UK credit card now and start building up a credit record. (I don't really know about that, just an idea.)
The loan amounts I've been finding up here in Scotland are for 3.75 to 4 times our salary, so that gives you a little more to play with.
I might suggest renting for a bit when you first move over, even if you had the money to buy, just to get used to the housing market, learn the areas, and look for the right deal.
Good luck, its a problem lots of people have.