For working in Slough, I will again recommend Ealing. (I accidentally recommended it to someone else in a different thread.) The commute could be done easily on National Rail and you would have much better access to central London if that is important to you. Ealing is brimming with single professionals of all ages and very multicultural.
I also know of a girl working in Slough who has chosen to live in Chiswick and drive to work via the M4. Again, you're commuting against the traffic so it's not so bad. She wanted to be closer to London and does not regret it at all.