My husband and I (that qualifies us as a family of 2) live in Birmingham, and make less than that. We rent a 3-bedroom house, but could probably afford a mortgage. We have one car, but probably could afford a second if I wanted to drive. We have some debt, but not a lot, and we do ok. We've been to the US twice this year, and manage to get away for long weekends in the Uk a few times a year. We don't go out a lot, so don't spend a lot that way.
So, with our kind of lifestyle, you'd have no problem with the amount you're talking about...