After Niall out grew most of his baby equipment, I started looking around for charities where I could donate these items. None of my local high street charities would take things like baby baths, swings, moses baskets, sterilzers, etc and most of the time, they weren't accepting clothing either.
I dislike leaving clothing in those big metal boxes at the supermarket because they rarely appear emptied and from what I can tell, our local ones leak horribly.
I asked my Health Visitor if she had any disadvantaged families in the area. Fortunately she did and she took several lots of clothing. I doubt that all Health Visitors would do that, but it may be worth asking because they will certainly know about families that are struggling.
After an afternoon of ringing round to local charities, I finally found a Catholic charity that works with single mothers in a shelter. They were more than happy to take the larger items.
As far as toys, have you checked with your local surgery or pre-school? They are sometimes more than happy to receive toys in good condition.