You have zero issues going to your home country. The only thing you require is a negative covid test up to 3 days before your flight. Or, proof from your doctor that you've recovered from previously having covid up to a certain point (think it's 3 months).
Your wife can join you with obviously the same covid conditions but will need to provide evidence such as your marriage certificate to prove she's exempt from the proclamation. It's also handy for her to have a copy of your passport bio page.
If your wife is travelling make sure she has her ESTA up to date, even though it'll likely be cancelled prior to the flight. Also, ensure you do
not check-in online prior to your flight to USA if travelling with your wife. This isn't a problem if travelling on your own.
Your wife can also travel to USA independently if required by ensuring she carries the evidence as above. Folk on this forum have done this.
So, in an answer, yes. You're fine with or without your wife