I can totally relate! While it's not a trans-Atlantic wedding we're planning, my fiancé and I live down in London. We're getting married in St. Andrew's in Scotland. We've arranged everything from down here, including all of the timing with coaches to pick-up everyone as they're flying in from England, the continent, and the US. We have also coordinated a day out in Edinburgh since several people are arriving early in the morning, when the check-in at the hotel isn't until 2:00PM. So they need something to do for a few hours. It's as if they're helpless without us. They couldn't even make their own hotel reservations. Like you, I don't have the most independent family and friends. They're quite sheltered.
My friends back in NY also wanted to throw me a bachelorette party, even though I am having a small hen night here. So I'm flying back to the US in a few days for that. (Thank goodness I have my frequent flier miles!)
As far as the honeymoon goes, if you plan to honeymoon in the Caribbean or someplace on that side of the world, it probably makes the most sense, both timing-wise and financially, to fly from the US. If you're honeymooning in Europe or the Mediterranean or someplace on that side of the world, it's probably best to fly from the UK.
I can totally relate to your frustrations. Hang in there!