It can be as simple as just an acute allergic reaction to laundry detergent or your clothing, but I've got a hypo thyroid problem, and I had bouts of itchy skin, and it started on the legs. It eventually went away, but after hydrocortisone anti-itch creme. The next area was on my lower abdomen, and finally, after many months of no-itching anywhere, I got a rash on my left arm, and by then I was living here. Went to the GP and was prescribed a tablet and a creme.