I'm sorry those have been your experiences rebduffy. Like Jewlz, I've had a very different experience here (although, I am also "Up North"), and I have a lot of friends who are southern (DH grew up there), and they are seriously the loveliest group of people I have ever met. Warm and friendly and just amazing. It is frustrating to move somewhere with different cultural triggers, though, could it be that you're somehow missing the cues that would let you know when people want to be your friend? I know I do that allll the time, and it does add to the confusion.
DH didn't really know any of his neighbours, but he is hardly ever home, and we live in a student heavy area, so they don't tend to stick around long. While I was looking for a job, I got to know a few of them, and I'm sure we could be friendlier if I did anything either than drag myself in the door and to bed each evening.