Being a college student at the moment, I'm still living at home with my mom. She can sometimes be extremely cautious about things and is concerned about me going by myself. She's explained that she personally wouldn't go on this trip alone, and she has travelled quite a bit.
I first went abroad when I was 20 and my mother was really uncomfortable about it. The only reason I was allowed to go was because it was with a university program so she figured I would at least have some support in the UK instead of just being on my own. But fact is, I travelled a lot on my own without the university. So I can understand the problem you're facing. It's not so much that she thinks something bad
will happen to you - it's the concern that she can't easily get to you
if something does. I think if you can check in with her once a day, that will put her at some ease. Having an itinerary of places you're staying, flights and train bookings that you can pass onto her will help as well. Make a small card with important contact information (i.e. 999 for emergencies, the number of the American Embassy, National Rail Enquries if you're taking trains) and let her know you'll be keeping it on you at all times. Maybe even made a few of them to keep in various bags/clothes just in case.
An important thing for her to know is that London takes tourists' safety seriously, especially with the Olympics approaching. (In fact, I almost find the concern about safety here to be a bit on the extreme ends at times!) Police are regularly patrolling tourist areas, train stations, etc. and the majority of Londoners will be more than willing to point you in the direction of help if you need any, not to mention there are maps all along roads and tourist areas to help keep you from getting lost.
It's definitely a trip worth making. Good luck with all your planning!