Lisa,
Andrew (not
my Andrew

--Bree's sociopathic son) has been out of the "juvenile delinquent school" for several episodes now. While he was there, he told his parents he thought he might be gay. Before that, in what led to a big plot twist, John's roommate had persuaded Carlos (Mr. Solis) to hire him to do the gardening, since John had been dismissed (the implication to the viewers being that, because he knew John had slept with Gabrielle, he thought if he worked for them, he might have a shot at her, too). He latered basically threatened to tell Carlos about her and John unless she slept with him. She said she was going to tell John he was trying to blackmail her and see what John had to say about it. The roommate then confessed that the real reason he wanted to sleep with her was because he was "afraid" he was gay--that he'd fooled around with a male friend of his and at first didn't think it meant anything, but was now starting to have feelings for him. So he thought he'd find out for sure whether he was gay or not if he slept with Gabrielle. Anyway, she listened sympathetically; told him that, if he was gay, there was no shame in it; said she wouldn't sleep with him but would be his friend; and started to leave. Then she turned around; gave him a long, passionate kiss; asked him if he felt anything/if the kiss did anything for him; he shook his head and said no; and she nodded in confirmation and said, "Gay" (very confident, that Gabrielle).

Fast forward an episode or two: Zach was having a pool party while his dad was out of town, and Susan (after Zach's previous threatening outburst with her when she wouldn't let him see her daughter) had forbidden her daughter from going to it. That night, two detectives showed up on Susan's doorstep and asked her to go to the police station with them so they could question her about Mike (regarding what she knew about him, in light of Mrs. Huber's bracelet being found in his garage and of the gunshot wound). While she was at the station, they showed her the file they had on him, which revealed that he'd been a heroin dealer, had served eight years in jail for killing a cop/manslaughter, etc. She broke up with him at the end of that episode, as a result.) Anyway, before that, when she got home from the police station, her daughter wasn't there, so she stormed over to Zach's to look for her. [Her daughter
had gone to the party earlier, but hadn't stayed for long. She had been sitting with Zach, and Andrew and his friends briefly took the piss out of Zach for being uncool. When Andrew turned away, Zach cocked his fingers as if they were a gun, started laughing and told Susan's daughter how easy it would be to kill Zach, that he knew where the gun his mom used to kill herself was, etc. Susan's daughter told him she didn't think that was funny--he said Andrew deserved it, she finally realized his elevator didn't go to the top floor, and she angrily left the party. She saw Bree's heartbroken daughter in front of Zach's house--John, the gardener, had just told her that he was seeing someone else and wasn't interested in her (she had been prepared to sleep with/lose her virginity to him to get his love, but Bree had found out and asked John to firmly tell her he wasn't interested). After all, John does love "Mrs. Solis"--I think it's very funny that, even after they've had an affair, he might be the father of her child, etc., he still calls her "Mrs. Solis," rather than her first name, as if she's his teacher--which I suppose she has been, in a way).

Anyway, Susan's daughter and Bree's daughter went for a walk, to talk things out, which is why she still wasn't home when Susan got back.]
Back to Susan: the party had more or less ended when she went looking for her daughter, and when she went to the back of the house, she spotted swimming trunks on the concrete next to the pool, as well as two people in a corner nook of the pool. She thought one was her daughter, and called out for her to get out of the pool. The two figures both ducked underwater, and Susan waited, since they had to come up for air sooner or later. So first John's roommate surfaced, gasping for air. Then she accused him of fooling around with her daughter (the person still underwater), at which point Andrew surfaced, gasping for air. Susan was stunned, apologetic; Andrew started saying it wasn't what she thought, etc.--awkwardness all the way around. It's
entirely too easy to get offtrack here with all the interweaving plot lines. Back to Andrew in a minute.
Anyway, Carlos is in even deeper sh-t now than he was to begin with because John's roommate is the second gay guy Carlos has beaten up after mistakenly thinking he was sleeping with his wife--the first was the cable guy, whom he attacked in the first or second episode. So from outward appearances, Carlos seems to be committing hate crimes--beating people up because they're gay--and hate crimes carry much heavier penalties.
Anyway, back to Andrew: As you might expect, Bree completely freaked out when Andrew said he thought he might be gay (even though, as they were leaving the disciplinary school, she hugged him and "thoughtfully" said, "I'd love you even if you murdered someone"). Once he was home, she blindsided him by inviting the family minister over to dinner, to have a "talk" with him. As the conversation turned to sexual preferences, Andrew said he was gay, period; he wasn't confused; there was nothing to talk about; and so on. (The dinner was a disaster--and when Rex defended Andrew over dinner, Bree blurted out that Rex had kinky S & M preferences, that she went along with them, and that was probably why Andrew was screwed up.)
Later that night, Bree was up late, browsing through Andrew's baby pictures, when he came downstairs to make a sandwich. He sat down next to her, and she told him that when she was giving birth to him, there were some serious complications (she had almost died), but she had told the doctor throughout that she didn't care what happened to her; she just wanted the baby to be okay. She told him she would have died for him then and would still do so, but she was terrified that she couldn't help him now. When he asked why, she tearfully said she was afraid he was going to go to hell (it was quite clear in the
Bible that homosexuality was a mortal sin, etc.).
The next day, he dropped by the minister's office and said he wanted to talk. He asked him if everything he said would remain confidential. The minister assured him that it would, and he told the minister he was there only to appease his mother. He also said he'd made his being gay up--that he'd only said he was gay to get his parents to take him out of the school. They talked in metaphors about preferring vanilla ice cream to chocolate ice cream, and Andrew said that he had tried one, then tried another, and just because he hadn't just stuck to one didn't mean he preferred the other....

Anyway, vengeful little SOB who he is, he told the minister that his mother telling him she thought he was going to go to hell had been his last straw with her. He said he was going to play the perfect son from then on: always being loving, courteous, polite, and helpful around the house; regularly going to church; not getting into any more trouble--the works. Then, when she absolutely least expected it, he was going to do something so out of the blue and horrific that it would destroy her to the core. (At the end-of-show wrapup, Bree's family was shown leaving church, with the minister greeting the congregation members as they left the building. Bree, Rex and the daughter all said hello as they walked by him, and Andrew was the last of the family to walk by. As he did he said, "Great sermon" or "Keep up the good work"--something like that--and gave the minister an evil smirk. (The minister looked appropriately troubled, but he can't say anything.)
Anyway, that's what made me wonder why Andrew wasn't in the last two or three episodes. I suspect that he's going to get his revenge on his mother by lying about how she treated his father/making her look guiltier than she already does (there's no way she'd strike back by telling the police that he ran over Mama Solis--she's too protective of him, and he knows it).
I don't think George will blackmail her--I suspect he'll try to insinuate his way back into her life again by being a loyal friend when her own children doubt her. (He'll probably set someone else up instead--Andrew, perhaps?--and, with any luck--in his mind, anyway--he'll get the girl in the end, after proving his steadfastness throughout). Just speculation.
You never know: maybe Rex (even though he's not a desperate housewife) will be the Mary Alice voiceover replacement for the second season, since solving the mystery around his death is obviously going to play a big role in next season's storyline(s). Again, just speculation.