I think a lot of the pros/cons will be highly dependent on individual circumstances. Personally, in my experience, the UK has provided a much better quality of life compared to the US.
Work/Life Balance
I have a very similar job in the UK, and my UK employer respects and encourages a better work/life balance compared to my previous US job. In the US, I worked longer core hours and was issued a company laptop, with the (unsaid but highly implied) expectation to work at home in the evenings and on weekends. In my organization in the UK, only the most senior level managers have the option (but not expectation) to be able to work at home or beyond core hours. A few months ago, there was even a whole campaign to address why employees were reporting putting in extra hours, and encouraging employees to finish on time, and leave work at work. Unless it was literally life/death, anything unfinished today could be picked up tomorrow. It was important to leave on time and have evenings at home with family, friends, and enjoying leisure activities. I appreciate the attention to this, and recognition of the importance of having a work/life balance.
Pay
Certainly, I was paid much more in the US. But for my circumstances, this didn't equate to actually having more disposable income. I have ongoing health issues (even before COVID hit), and most of my expenses outside of living costs were eaten up by medical bills. And this was even with a good insurance plan through my employer. Granted, I don't know how it would be today since quite a few insurance reforms have been passed, but at the time, medical expenses could be significant even with a good insurance plan. I barely had savings in the US, despite my pay being 2-3x higher. I have a comfortable financial safety net here in the UK, mostly due to not having to pay for medical stuff and actually being able to save.
Sick Days and Holidays
At my US job, I had 7 days of paid sick leave per year. I also had a "generous" 15 days of annual leave per year. If I recall correctly, you could buy more annual leave, to be deducted from your salary, but it was capped at 5 extra days per year. Many of my US friends (in other jobs) had 10 days of annual leave, and that would increase to 20 days after 10 years of service. They did not have an option to purchase additional leave.
Where I am now in the UK, the starting entitlement to annual leave is 27 days (though now I'm at 33 days). I also started at 1 month full paid sick leave (and 2 months half paid), and am now up to 6 months full paid sick leave (and then another 6 months half).
Job Loss
I was once let go in the US, and had 3 hours to pack my things, turn in my badge, and leave. I was asked to bring a copy of a specific report to the office (nothing unusual), and when I got there, my manager was sitting there with an HR rep. I was told I was being let go. I wasn't given any reason. Emotionally and financially, it was devastating. I never had any negative feedback, no meetings to discuss my performance, no indication that I needed to improve anything. Just, bye. I had been supervising others, and when I let them know, they were all completely surprised. To this day, I don't know exactly what happened. There was no transparency.
At my next job (in the US), the process of termination was definitely more laid out. You knew the roadmap. So it's not a whole-US thing, but it (totally out of the blue job loss) can happen.
Where I am now in the UK, it seems almost impossible to be outright fired unless you're doing something exceptionally naughty. I can't speak for all jobs, but it seems that there are a lot more protections before a termination occurs.
Healthcare
By far, this is the huge thing for me. Due to the huge cost of healthcare in the US, I actually feel that the door to returning to the US has been closed for me unless I become a multi-millionaire. One night in A&E cost me $12k, with insurance, because they found something that happened to me as a kid that they considered a pre-existing condition. I had completely forgotten about it; I was that little at the time.
I have a family member who can't afford a great insurance package, and has gone to a veterinarian for some basic treatments (e.g., removing stitches) because the vet was cheaper than a doctor. I have a friend who would dearly love to quit her job, and feels trapped because she wouldn't be able to afford the equivalent health insurance package in another job (or one wasn't offered to the same coverage level).
IMO, it's very comforting knowing that no matter your employment status or financial ability, you can access "free" healthcare in the UK.
Education
I don't have kids, nor have I personally been through the UK education system, but it's my impression that the US system has more variability in regards to quality than the UK. Where I grew up, you need at least a Master's degree to teach. In Arizona, you don't need a degree to have been awarded yet (any degree). I'm not implying that degrees equate to quality, but more as an example of variability. I'm sure there's also variability in the UK, but it seems that DFE seems to intervene more than a board of education might in the US? (this is just my impression though)