A quick google search tells me that most airlines do have procedures for unaccompanied international travel. On most airlines, a 12-year-old is not required to travel as an unaccompanied minor, but can do so. So, the airlines do have the infrastructure in place. So, when booking the flight, you will have to speak with the airline. I have no advice on any additional requirements on either side of the pond. Perhaps someone else can comment.