Hi Brigette,
Sounds as though you've got it much easier to move 'back' here as you already have your citizenship! which is definitely a bonus..
All the replies are of course positive and based on those individuals feedback, but overall, yes, Manchester is a vibrant city and a good choice for anyone moving into the country.
You've mentioned a couple times about securing a job prior to moving. This is indeed possible, and has been done by many countless times. However, it all depends on what your job field is, if there's any vacancies you can go for etc. There's no mistaking things currently, and the job situation is dire all over the UK, there are more applicants chasing each opening than ever before. That's not to say they're all good suitable candidates though! What line of work are you in? how much experience do you have? would you need to back things up with study/qualifications etc etc.. I suspect, you'll need to move your focus away from 'moving to manchester' which you now know is indeed a good place to live, and more towards what job you can get or go for and crucially, what kind of salary level you'll realistically get. I know it's boring and not what you 'want' to hear, but it is fundamental to what you seem to be wanting short, medium and long term. If you are indeed able to secure a job prior to moving, you'll feel more reassured once you land here, if not, then you'll need to be making plans now and saving up as much money as you can to look after yourself once here and jobhunting.
Good luck !
Cheers, DtM! West London & Slough UK!