Whose income are you using to meet the financial requirement for the visa?
If it’s her income, she will need to stay at her current job until after her visa is issued, so that she continues to meet the visa requirements while it is processing.
However, if you’re using your income for the visa and not hers, then she is free to change jobs while waiting for the visa to be processed. The hurdle however may be getting a company to hire her while she has a visa pending, given that she won’t have evidence of a current valid visa.
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