Yeah, I'm finding that 20s is such a weird time for social circles. My friends back in the US sort of have Peter Pan syndrome. They don't totally act like teenagers, but they're not really interested in settling down either. Only the ones with "real jobs" tend to get home by midnight, but otherwise they all just go out to gigs, get drunk, go back to someone's house, listen to records and drink more. Most of them are musicians, though, so that could have something to do with it.
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More of my friends here are happy to have a couple of pints or cocktails and go home. Some of them do like to have a sloppy night out every once in a while (which I won't begrudge them, but I'm happy not to tag along), but they're the ones who are Scottish and already have friends from high school here that they can do that with.
My circle of friends here was formed from all of us being on the same postgraduate course. I think since we all had to act like "colleagues" while we were in uni, we tend to keep it relatively low key when we're together. You know, informal dinner parties, going out for a couple of drinks, etc. Half the time we end up talking business, like jobs, research, etc. Of course, there have been a couple of nights when we all drank a little too much, but it was celebratory, and no one ended up puking or crying or lost their shoes or any of that random stuff that happens on seriously drunk, dramatic nights.
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Ultimately, people are going to do what they want to do, and like anything else, some friendships will run their course, or change. The best you can do is find some kind of happy medium and maybe make better friends with those nerds!
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